Article

An Abbreviated History of Beta-Glucan

Published: 10:54 AM, January 30, 2026

And why CM-Glucan is its next evolution

Long before immunity became a daily conversation, the human body already knew how to defend itself— thanks in part to natural compounds that support immune balance. One of the  most researched among them is beta-glucan.

From traditional remedies to modern science, beta-glucan’s story is one of steady evolution—culminating today in its advanced form: CM-Glucan.

Early Beta-Glucan: Nature’s Original Defense

Beta-glucan is found naturally in the cell walls of yeast, oats, barley, and certain mushrooms. These sources have been part of human diets and healing practices for thousands of years. Ancient cultures may not have known the science behind beta-glucan, but they understood its effects.

In traditional medicine, mushroom extracts were used against illness. Whole grains like barley and oats were valued for their ability to help the body recover and stay resilient. What these practices had in common was beta-glucan, a compound that works by interacting with the immune system rather than overstimulating it.

Scientific Discovery: From Observation to Evidence 
(1940s–1980s)

Modern science began paying closer attention to beta-glucan in the mid-20th century. Researchers in the 1940s first identified beta-glucan’s structure and observed how it interacted with immune cells. By the 1970s and 1980s, studies showed that beta-glucan could activate key immune responses, particularly macrophages and natural killer cells—frontline defenders of the immune system.

What made beta-glucan unique was its ability to support immune balance. Rather than forcing the immune system into overdrive, it helps regulate immune response.

Popularization: The Rise of Supplements 
(1990s–Present)

As immune health became a growing priority, beta-glucan entered the mainstream. In 1997, the US Food and Drug Administration (FDA) approved the first health claims relating to oats, marking a shift from traditional food sources to targeted immune support.

By the late 1990s and early 2000s, beta-glucan supplements became more widely available, though not all forms were equally effective. And in 2009, it earned further credibility when the European Food Safety Authority (EFSA) recognized health benefit claims for oat beta-glucans.

CM-Glucan: The Next Evolution

Scientific progress didn’t stop at discovery—it led to CM-Glucan, an advanced form of beta-glucan developed through a Swiss-patented process. By modifying the molecular structure, CM-Glucan becomes up to 100x more absorbable than Standard Beta-Glucan.

Immunomax is made with pure CM-Glucan, a natural immunomodulator proven to produce more antibodies than Vitamin C, and helps support immune balance with proper diet and exercise. 

From ancient grains and mushrooms to cutting-edge Swiss innovation, the story of beta-glucan is one of progress. And with CM-Glucan, that progress continues to advance.

MAHALAGANG PAALALA: Ang Immunomax at Immunomax Forte ay hindi gamot at hindi dapat gamiting panggamot sa anumang uri ng sakit.

ASC Reference No. I0025N011926I


You might also like

View all Related

3 Crucial Bodily Functions that Impact your Immune System

October 21, 2025

Some things are beyond your control, but there are ways you can fight back. Your immune system is constantly working to protect you from bacteria, viruses, and other harmful invaders. But like any part of the body, it’s influenced by many factors.